Newsletter | October 20, 2025

10.20.25 -- Unlocking Precision In AAV Titer Measurement

Measuring AAV Vector Genome Titer Using Droplet Digital PCR Protocol

Learn an optimized protocol for precisely measuring AAV vector genome titer. The ddPCR method offers lower variability than qPCR, ensuring consistency across your cell and gene therapy manufacturing workflow.

 

Adeno-Associated Virus: Enabling Genomic Medicine

Since the first rAAV-based therapy was approved by the FDA, the application of gene therapies utilizing rAAV vectors has expanded rapidly. Learn about the history of AAV, their clinical applications, biology, manufacturing, and quantification.

 

VIDEO INSIGHTS

Compare How Two Types Of Technology Measure AAV Viral Titer

Examine the differences between ddPCR technology and plate-based digital PCR technologies. Watch this video to compare the abilities of both when measuring AAV viral titer.

 

The Gold Standard: Droplet Digital PCR

Droplet Digital PCR (ddPCR) is a method for performing digital PCR that is based on water-oil emulsion droplet technology. A sample is fractionated into 20,000 droplets, and PCR amplification of the template molecules occurs in each individual droplet. Check out what Bio-Rad customers have to say about using ddPCR.